Which of the following routes can Labetalol be administered?

Labetalol is a medication that can be administered through multiple routes, specifically intravenous (IV), intraosseous (IO), and oral (PO). This flexibility in administration is beneficial in various clinical settings. The intravenous and intraosseous routes allow for rapid onset of action, which is especially useful in acute situations requiring quick blood pressure control, such as hypertensive emergencies. The oral route provides an alternative for ongoing management of hypertension in a less acute setting, allowing for patient self-administration at home or in outpatient situations.

The other routes mentioned—intramuscular (IM), subcutaneous, and inhalation—are not viable options for Labetalol administration, as they do not provide the same effectiveness or desired pharmacokinetic profile for this specific medication. IM and subcutaneous routes are generally used for other medications, while inhalation is not an appropriate method for delivering Labetalol's therapeutic effects.