What effect does Atropine have on the cough reflex?

Atropine has an anticholinergic effect, meaning it blocks the action of acetylcholine, a neurotransmitter that plays a significant role in activating many bodily functions, including the cough reflex. By inhibiting the vagus nerve's influence, which mediates that reflex, atropine diminishes the cough reflex. It can lead to reduced secretions in the respiratory tract as well, further contributing to a less responsive cough reflex. This property is particularly useful in clinical scenarios where an overly active cough may be detrimental or uncomfortable for the patient, such as managing respiratory conditions or during certain surgical procedures where cough suppression is desired.