What adverse effect is associated with Amiodarone related to the heart's electrical activity?

Amiodarone is an antiarrhythmic medication commonly used to manage various types of cardiac arrhythmias. One of its well-documented adverse effects is the prolongation of the QT interval on the electrocardiogram. The QT interval measures the time it takes for the heart's electrical system to reset after each heartbeat. When this interval is prolonged, it can lead to serious arrhythmias, including Torsades de Pointes, which is a potentially life-threatening condition.

Prolonged QT interval can result from several factors, including drug interactions, electrolyte imbalances, or direct effects of the medication on cardiac ion channels responsible for repolarization. This makes it crucial for healthcare providers to monitor patients on Amiodarone for any signs of changes in cardiac rhythms and to perform regular ECG assessments.

While other options pertain to various heart conditions or effects, they do not specifically highlight Amiodarone's known tendency to cause QT interval prolongation, making this adverse effect a critical aspect of safe drug management in patients taking this medication.